E2A in Mehsana
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Pre Instructions
Recommended by Health Experts
NABL Accredited Labs
Age Group 05-90 years
Recommended for Men, Women
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E2A1
FAQ
What is the role of Activating Transcription Factor 3 (ATCF 3)?
ATF3 functions as an oncogene or tumor suppressor in prostate cancer which is upregulated by androgen and helps in inducing the cell proliferation and G1-to-S-phase transition of the cell cycle.
What is the role of transcription factors in leukemia?
In bone marrow, transcription factors such as E2A proteins control essential genes to maintain the normal hematopoietic system.
Why should I book the E2A Test with Sterling Accuris?
Sterling Accuris Diagnostics specializes in providing quick and reliable diagnosis support across numerous specialties. It is effortless to book the E2A Test with us, giving you accurate results at a great price. Sterling Accuris also provides a safe home collection for your convenience.
Do transcription factors interact with proteins?
Transcription factors are vital molecules that play a major role in controlling gene expression and proteins possessing domains. This helps in proteins binding to the DNA of the promoter or enhancer regions of specific genes for its regulation.
What other packages does Sterling Accuris offer?
Sterling Accuris offers a range of packages including Senior citizen (male and female) package, healthy heart profile, diabetes profile, vitamin profile, covid immunity package and much more. Visit our website to learn more about these packages.
What makes Sterling Accuris a better pathology lab than others?
For us, precision care, safe sample collection, timely delivery of reports, and precise reporting of patient results while adhering to health and safety precautions are the cornerstone of our success.
Do you provide home visit/collection service?
Yes. We do provide home collection services at your doorstep.
Please go ahead and book your visit today from our top menu options in this website / chat or do call us on 812 813 0000.
How long does it take to receive test results?
Though most tests are completed and reported within about 24 hours of receiving the sample for testing, certain tests take several days to weeks.
Your soft copy will be sent on registered email id and Whatsapp. Also, you will receive SMS with link to download your report. Also, your report is available on our website / app.
To know the status of the report, you can call our customer care team on 812 813 0000.
Is there any preparation or precautions for patient before tests or body checkup?
Fasting maybe required in case of a few tests to ensure accurate results.
In general, it is also advisable to abstain from alcohol and heavy diet at least for 24 hours before any health test. You can see the requirement for each test on the product page on our website / app.
E2A Test in Mehsana
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Sterling Accuris Diagnostics offers the E2A Test in Mehsana to study chromosome translocation, transcriptional factor 3 (TCF 3), and gene rearrangements in lymphoid malignancies.
Overview of the E2A Test
The Fluorescence in Situ Hybridization (FISH) technique is used to study chromosome structure and function for DNA analysis and chromosomal investigation. The transcription factor 3 (TCF3) gene, also called E2A, is a protein that comprises two related basic helix–loop–helix named E12 and E47 that differ in their DNA-binding region. The E2A gene encodes a member of the E protein (class I) family of helix-loop-helix transcription factors that plays a critical role in lymphopoiesis and B and T lymphocyte development. Deletion of this gene or encoded protein may play a significant role in lymphoid malignancies like pre-B-cell acute lymphoblastic leukemia.
Book an E2A Test Near You to study chromosome translocation, transcriptional factor 3 (TCF 3), and gene rearrangements in lymphoid malignancies. You can rely on Sterling Accuris Diagnostics for E2A Test in Mehsana for accurate test results.
Why and When is the E2A Test conducted?
The E2A test is done to study the chromosomal translocation and gene rearrangement, which can occur in patients with a suppressed immune system or plasma disorder and a family history of bone marrow cancer. The E2A test is conducted when the doctor suspects the following conditions:
- Lymphoid Malignancies
- Agammaglobulinemia 8B
- Agammaglobulinemia 8A
- Burkitt’s Lymphomas
- Multiple Myeloma
- Chronic Leukemia
Furthermore, a doctor may ask the person to take E2A Test if the person experiences the following symptoms:
- Enlarged liver or spleen
- Swollen lymph nodes
- Leukemia type condition
- Losing excessive weight
- Easy bleeding
- Recurrent nosebleeds
- A feeling of fullness in the stomach
- Chest or lower back pain
- Rash or itching
- Excessive sweating, especially at night
- Bone pain or tenderness
E2A Test: Main Highlights
- Instructions: No fasting is required
- Recommended Age: All age groups
- Sample type for test: Bone Marrow and Blood sample in a sodium heparin tube (leukemic blood)
How to interpret the E2A Test Report
The Fluorescent in situ hybridization (FISH) assay is the standard tool for detecting E2A protein-related chromosomal translocations. It is a vital tool in selecting a targeted therapy for different leukemias. Fluorescent in situ hybridization (FISH) is a genetic technique that can also be used to diagnose:
- Congenital diseases
- Detection of HER2 gene in breast cancer surgery
- Acute lymphocytic leukemia
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