Best Pathology Lab in India for Blood Test & Full Body Checkup Test Slash JAK2 V617F with reflex to Exon 12 in Adipur

JAK2 V617F with reflex to Exon 12 in Adipur

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JAK2 V617F with reflex to Exon 12
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FAQ

What makes V617F and JAK2 Exon 12 different from one another?

Erythrocytosis in PV and thrombocytosis in ET can both result from the JAK2p V617F mutation, whereas erythrocytosis is the only symptom of JAK2 exon 12 mutations.

What occurs if JAK2 is positive?

A person is more likely to have a Myeloproliferative Neoplasm (MPN) if they test positive for the JAK2 V617F mutation.

Is JAK2 a blood disorder?

Myeloproliferative neoplasm (MPN), a preleukemic blood condition, is caused by the activating JAK2-V617F mutation.

Why should I book JAK2 V617F with a reflex to Exon 12 Test with Sterling Accuris Diagnostics?

Sterling Accuris Diagnostics is at the forefront of pathology services in India, with international quality standards. Our NABL-accredited laboratory specializes in providing quick and reliable primary diagnosis support for hospitals, physicians and other healthcare facilities across the country. We even offer home collections for a JAK2 V617F with a reflex to Exon 12 Test in Adipur.

It is extremely convenient to book a JAK2 V617F with a reflex to Exon 12 Test with us that would give you accurate and precise results at a great price.

What makes Sterling Accuris a better pathology lab than others?

For us, precision care, safe sample collection, timely delivery of reports, and precise reporting of patient results while adhering to health and safety precautions are the cornerstone of our success.

What other packages does Sterling Accuris offer?

Sterling Accuris offers a range of packages including Senior citizen (male and female) package, healthy heart profile, diabetes profile, vitamin profile, covid immunity package and much more. Visit our website to learn more about these packages.

Do you provide home visit/collection service?

Yes. We do provide home collection services at your doorstep.

Please go ahead and book your visit today from our top menu options in this website / chat or do call us on 812 813 0000.

Is there any preparation or precautions for patient before tests or body checkup?

Fasting maybe required in case of a few tests to ensure accurate results. 

In general, it is also advisable to abstain from alcohol and heavy diet at least for 24 hours before any health test. You can see the requirement for each test on the product page on our website / app.

How long does it take to receive test results?

Though most tests are completed and reported within about 24 hours of receiving the sample for testing, certain tests take several days to weeks.

Your soft copy will be sent on registered email id and Whatsapp. Also, you will receive SMS with link to download your report. Also, your report is available on our website / app.

To know the status of the report, you can call our customer care team on 812 813 0000.

JAK2 V617F with a reflex to Exon 12 Test in Adipur

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Sterling Accuris Diagnostics offers the JAK2 V617F with a reflex to Exon 12 Test in Adipur   to diagnose Polycythemia Vera (PV). 

Overview of JAK2 V617F with a reflex to Exon 12 Test

This qualitative test can identify the JAK-2 V617F mutation in platelets and granulocytes from ET patients. A key component in regulating the production of white blood cells from hematopoietic stem cells is the non-receptor tyrosine kinase known as Janus kinase 2 (JAK-2). Conditions like Essential Thrombocythemia(ET), Polycythemia Vera(PV), and Primary Myelofibrosis(PMF) are caused by the V617F mutation in JAK-2, which causes abnormal blood cell growth. These mutations are all found in exons 12 through 15. 

For accurate and precise test results head on to Sterling Accuris Diagnostics for the JAK2 V617F with a reflex to Exon 12 Test in Adipur

Why and when is the JAK2 V617F with a reflex to Exon 12 Test done?

Doctors use this test to identify and diagnose Polycythaemia Vera (PV), a form of myeloproliferative disease. It was formerly limited to PV cases alone, but it is now also used to test individuals who have a suspicion of PV but are V617F negative. 

JAK2 V617F with a reflex to Exon 12 Test: Main Highlights

  • Instructions: Form 20 (Genomics Clinical Information Requisition Form) must be properly completed.
  • Recommended Age: Above 50 years of age.
  • Sample type for test: Blood EDTA

Understanding how to interpret JAK2 V617F with a reflex to Exon 12 Test Reports 

One of the following three states will represent the results:

  • Positive for the V617F mutation in JAK2.
  • Positive for the JAK2 mutations other than V617F
  • JAK2 mutations are absent.

A description of the nucleotide-level mutation and the changed protein sequence are given if the test is positive.

A Polycythemia Vera diagnosis may be supported in the proper clinical circumstances by a positive mutation status, which strongly suggests a myeloid neoplasm.

A diagnosis of Polycythemia Vera, other myeloproliferative neoplasms, or other neoplasms is highly improbable if the mutation status is negative, but it does not entirely rule out this possibility.

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