HLA Typing Class I & II (Molecular Method) in Ahmedabad

Sterling Accuris Diagnostics offers the HLA Typing Classes I and II (Molecular Method) Test in Ahmedabad to evaluate transplant compatibility.

Overview of HLA Typing Classes I and II (Molecular Method) Test

Cell surface proteins that control the immune system are part of the human leukocyte antigen (HLA) complex. Although the loci that encode for HLA are the same in every person, there are numerous potential alleles that could be expressed at each of the more than 34,000 loci that have been identified. Molecular polymerase chain reaction (PCR)-based HLA typing techniques allow the determination of DNA sequence variations, either by hybridization with sequence-specific oligonucleotide probes (PCR-SSO), by a combination of sequence-specific primers (PCR-SSP), or by direct sequencing of the PCR product.

Get a HLA Typing Classes I and II (Molecular Method) test near you to rule out any further complications that may lead to serious diseases. For accurate and precise test results head on to Sterling Accuris Diagnostics for the HLA Typing Classes I and II (Molecular Method) Test in Ahmedabad

Why and when is the HLA Typing Classes I and II (Molecular Method) Test done?

In order to evaluate transplant compatibility, the doctor typically advises laboratory testing for HLA because different people may have extremely varied HLA alleles, which may induce alloreactivity between recipients and donors. In addition to its application in transplantation, laboratory testing for HLA may be used in pharmacogenetics to assess disease associations, determine the risk of an adverse reaction to particular medications, support platelet transfusion, or analyse disease associations.

HLA Typing Classes I and II (Molecular Method) Test: Main Highlights

• Instructions:No specific special preparation is required for this test.
• Recommended Age: Any age group
• Sample type for test: Blood, buccal swabs, biopsy samples, and frozen tissue.

Understanding how to interpret HLA Typing Classes I and II (Molecular Method) Test Reports

HLA antibody positivity indicates a poor match between a potential donor and recipient when results are compared. Specific proteins that HLA antibodies see as foreign are targeted. The body is likely to reject the organ if the proteins and antibodies between a donor and receiver are incompatible.

FAQs

What distinctions can be made between HLA typing at low and high resolutions?

The term "high resolution" in human leukocyte antigen (HLA) typing describes the amount of data that is produced by molecular typing techniques. The locus and allele group are disclosed by low-resolution typing.

 How do you define graft versus host disease (GVHD)?

When a patient receives a transplant from an unrelated donor, the disease known as GVHD might develop if the HLA matching is not perfect. Immune cells from the transplanted donor lymphocytes begin to target the recipient's cells and tissues that appear "foreign."

 Why should I book HLA Typing Classes I and II (Molecular Method) Test with Sterling Accuris Diagnostics in Ahmedabad?

Sterling Accuris Diagnostics is at the forefront of pathology services in India, with international quality standards. Our NABL-accredited laboratory specializes in providing quick and reliable primary diagnosis support for hospitals, physicians and other healthcare facilities across the country. We even offer home collections for a HLA Typing Classes I and II (Molecular Method) Test in Ahmedabad.

It is extremely convenient to book a HLA Typing Classes I and II (Molecular Method) Test with us that would give you accurate and precise results at a great price.