Best Pathology Lab in India for Blood Test & Full Body Checkup Test Slash JAK2 V617F Mutation by Sanger in Ahmedabad

JAK2 V617F Mutation by Sanger in Ahmedabad

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JAK2 V617F mutation by Sanger
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FAQ

Can JAK2 cause cancer?

JAK2 mutations have been found in ALL and other hematopoietic cancers. The most common tumours when JAK2 is changed include lung adenocarcinoma, myeloproliferative neoplasm, breast invasive ductal carcinoma, polycythemia vera, and colon adenocarcinoma.

How serious is a JAK2 mutation?

Despite being uncommon, JAK2 mutations can be uncomfortable and distressing. Even though PV and ET are often less severe conditions, they can progress to PMF, which is regarded as a blood cancer.

Why should I book JAK2 V617F Mutation by Sanger Test with Sterling Accuris Diagnostics?

Sterling Accuris Diagnostics is at the forefront of pathology services in India, with international quality standards. Our NABL-accredited laboratory specializes in providing quick and reliable primary diagnosis support for hospitals, physicians and other healthcare facilities across the country. We even offer home collections for a JAK2 V617F Mutation by Sanger Test in Ahmedabad.

It is extremely convenient to book a JAK2 V617F Mutation by Sanger Test with us that would give you accurate and precise results at a great price.

What makes Sterling Accuris a better pathology lab than others?

For us, precision care, safe sample collection, timely delivery of reports, and precise reporting of patient results while adhering to health and safety precautions are the cornerstone of our success.

What other packages does Sterling Accuris offer?

Sterling Accuris offers a range of packages including Senior citizen (male and female) package, healthy heart profile, diabetes profile, vitamin profile, covid immunity package and much more. Visit our website to learn more about these packages.

Do you provide home visit/collection service?

Yes. We do provide home collection services at your doorstep.

Please go ahead and book your visit today from our top menu options in this website / chat or do call us on 812 813 0000.

How long does it take to receive test results?

Though most tests are completed and reported within about 24 hours of receiving the sample for testing, certain tests take several days to weeks.

Your soft copy will be sent on registered email id and Whatsapp. Also, you will receive SMS with link to download your report. Also, your report is available on our website / app.

To know the status of the report, you can call our customer care team on 812 813 0000.

Is there any preparation or precautions for patient before tests or body checkup?

Fasting maybe required in case of a few tests to ensure accurate results. 

In general, it is also advisable to abstain from alcohol and heavy diet at least for 24 hours before any health test. You can see the requirement for each test on the product page on our website / app.

JAK2 V617F Mutation by Sanger Test in Ahmedabad

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Sterling Accuris Diagnostics offers the JAK2 V617F Mutation by Sanger Test in Ahmedabad to detect Polycythemia Vera and to differentiate between different myeloproliferative neoplasms. 

Overview of JAK2 V617F Mutation by Sanger Test

Tyrosine kinase (JAK2), which is produced by the Janus kinase 2 (JAK2) gene, is related to the cytoplasmic region of a number of transmembrane cytokine and growth factor receptors that are important in signal transduction in hematopoietic cells. In 50% to 60% of primary myelofibrosis, in 95% to 98% of essential thrombocythemia, and in 50% to 60% of polycythemia vera (PV), the JAK2 V617F mutation is found in exon 14. These mutations consist of minor insertions or deletions as well as point mutations.

Sanger sequencing of JAK2 exons 12–15 will be carried out on the stored RNA sample. No additional testing will be carried out if a JAK2 V617F mutation (>0.6%) is found. RNA and DNA are both extracted. The extremely sensitive DNA-based JAK2 V617F test using an allele-specific polymerase chain reaction forms the basis of the algorithm. The JAK2 exons 12 through the first 90% of exon 15, which span the region retaining nearly all mutations described in myeloproliferative neoplasms, are covered by Sanger sequencing.

Get a JAK2 V617F Mutation by Sanger test near you to rule out any further complications that may lead to serious diseases. For accurate and precise test results head on to Sterling Accuris Diagnostics for the JAK2 V617F Mutation by Sanger Test in Ahmedabad

Why and when is the JAK2 V617F Mutation by Sanger Test done?

Doctors use this test to identify and diagnose polycythaemia vera (PV), a form of myeloproliferative disease. It was formerly limited to PV cases alone, but it is now also used to test individuals who have a suspicion of PV but are V617F negative. It also helps to distinguish between myeloproliferative neoplasms, polycythemia vera, and secondary erythrocytosis.

JAK2 V617F Mutation by Sanger Test: Main Highlights

  • Instructions: Form 20 (Genomics Clinical Information Requisition Form) must be properly completed.
  • Recommended Age: Any age group.
  • Sample type for test: Blood (EDTA)

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