Best Pathology Lab in India for Blood Test & Full Body Checkup Test Slash Chromosome 17p deletion in Dakor

Chromosome 17p deletion in Dakor

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Chromosome 17p deletion
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FAQ

What is cytogenetic abnormality?

The change that occurs at the DNA/genetic level is called cytogenetic abnormality. Cytogenetics utilises advanced laboratory techniques to identify small changes in chromosomes that contain genes. Any chromosomal abnormalities like broken, missing, rearranged, or extra chromosomes can be detected by cytogenetic techniques. Some common cytogenetic abnormality-associated diseases are multiple myeloma, Down’s syndrome, chronic lymphocytic leukaemia etc.   

What is multiple myeloma?

Multiple myeloma is one of the most common cancers of B-cells in blood that arises due to chromosome 17p deletion. The gene involved is TP53 that is one most important risk factor for this disease. The disease characterised by:

  • Bone-pain
  • Weight-loss
  • Fatigue
  • Numbness in legs
  • Anaemia
  • Prone to infections
  • Hypercalcemia
  • Episodes of bleeding

What tests are used to detect genetic abnormalities in pre-natal stage?

Besides the traditional chromosome G-banding technique, there are many advanced molecular diagnostic tests available for testing genetic changes at pre-natal stage like: Fluorescent InSitu Hybridization, Chromosomal Microarray, SNP analysis, PCR for DNA fragment size analysis, etc.

Why should you book the Chromosome 17p deletion - FISH Test with Sterling Accuris?

Sterling Diagnostics uses the best facilities to provide accurate results. Book Chromosome 17p deletion - FISH  Test in Dakor with us for timely results.

What makes Sterling Accuris a better pathology lab than others?

For us, precision care, safe sample collection, timely delivery of reports, and precise reporting of patient results while adhering to health and safety precautions are the cornerstone of our success.

What other packages does Sterling Accuris offer?

Sterling Accuris offers a range of packages including Senior citizen (male and female) package, healthy heart profile, diabetes profile, vitamin profile, covid immunity package and much more. Visit our website to learn more about these packages.

Do you provide home visit/collection service?

Yes. We do provide home collection services at your doorstep.

Please go ahead and book your visit today from our top menu options in this website / chat or do call us on 812 813 0000.

Is there any preparation or precautions for patient before tests or body checkup?

Fasting maybe required in case of a few tests to ensure accurate results. 

In general, it is also advisable to abstain from alcohol and heavy diet at least for 24 hours before any health test. You can see the requirement for each test on the product page on our website / app.

How long does it take to receive test results?

Though most tests are completed and reported within about 24 hours of receiving the sample for testing, certain tests take several days to weeks.

Your soft copy will be sent on registered email id and Whatsapp. Also, you will receive SMS with link to download your report. Also, your report is available on our website / app.

To know the status of the report, you can call our customer care team on 812 813 0000.

Chromosome 17p Deletion - FISH Test in Dakor

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Sterling Accuris Diagnostics offers the Chromosome 17p deletion - FISH Test in Dakor to detect cytogenetic abnormalities on chromosome 17 and related disease like chronic lymphocytic leukaemia.    

Overview of the Chromosome 17p deletion - FISH Test (By Fluorescent In Situ Hybridization) 

The Chromosome 17p deletion - FISH Test is performed to detect the loss of DNA segments from the short arm of chromosome 17. Chromosome 17 contains the code for the TP53 gene, a tumour suppressor gene. It is involved in diverse cellular processes and plays an essential role in cell division and in damaged DNA repair. The deletion in chromosome 17p can result in severe diseases like multiple myeloma, chronic lymphocytic leukaemia (CLL), acute lymphocytic leukaemia, etc.

Sterling Accuris Diagnostics offers an accurate Chromosome 17p deletion - FISH Test in Dakor.     

Why And When Is A Chromosome 17p deletion - FISH Test Done?

The Chromosome 17p deletion - FISH Test is a frequent event in several malignancies like leukaemia, myeloma, etc. This test is done at both the pre-natal and post-natal stage. At pre-natal stage, it is particularly referred for high risk conditions, and at the post-natal stage to detect the reasons for developmental delays.   

A doctor may recommend the test when a person shows following the symptoms:

Pre-natal stage:

  • More than 40 years of the pregnant women
  • One or more past miscarriage
  • Slow foetal growth
  • Foetal anomalies detected by ultrasound 

Postnatal stage:

  • Developmental delays
  • Heart defect
  • Reduced muscle growth
  • Atypical facial character 

Chromosome 17p deletion - FISH Test: Main Highlights

  • Instructions: Fasting is not required
  • Recommended age group: All age groups
  • Sample type: Blood sample in EDTA tube

How to interpret the Chromosome 17p deletion - FISH Test Report

The Chromosome 17p deletion - FISH Test is done with a technique called Fluorescent InSitu Hybridization (FISH). In this technique fluorescently labelled probes bind with single stranded sample DNA/RNA. The samples are then subjected for fluorescence microscopic analysis to identify the deletion chromosome 17p region.

The fluorescent intensity after is read as output given as:

  • Normal- 2 orange and 2 green signals are captured/visualised
  • Chromosome 17p deletion – 1 orange and 2 green signals are captured/visualised

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