Best Pathology Lab in India for Blood Test & Full Body Checkup Test Slash MSI Study (Micro Satellite Instability) IHC in Dakor

MSI Study (Micro Satellite Instability) IHC in Dakor

Includes 8 parameters
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Specimen Histo, Clinical Diagnosis Histo, Gross Description Histo, Microscopic Description Histo, IHC New, Diagnosis Histo, Comments Histo, Note Histo
Pre instruction

Pre Instructions

Test Parameter Included 8 Parameter
Profile No. of Parameters
  • Specimen Histo 1Specimen Histo
  • Clinical Diagnosis Histo 1Clinical Diagnosis Histo
  • Gross Description Histo 1Gross Description Histo
  • Microscopic Description Histo 1Microscopic Description Histo
  • IHC New 1IHC New
  • Diagnosis Histo 1Diagnosis Histo
  • Comments Histo 1Comments Histo
  • Note Histo 1Note Histo

FAQ

What are the four core microsatellite markers assessed in MSI?

The five core markers recommended for testing are MLH1, MSH2, MSH6 and PMS2.  

What are the ways in which MSI testing can be done?

MSI testing can be done either using fluorescently labelled primers to amplify DNA fragments of the tumour samples. Another way is immunohistochemistry (IHC) in which tissues are labelled with fluorescently labelled antibodies against the mismatch repair proteins in the tissue samples.  

How is microsatellite instability assessed?

Microsatellite instability is done to identify the tumours that result due to mutation in the mismatch repair genes. MSI is detected by comparing the number of nucleotides repeated in the microsatellite marker of normal tissue with that of the tumour tissues of the patient.   

Why should you book an MSI Study (Microsatellite Instability) IHC test with Sterling Accuris?

Sterling Accuris specialises in providing quick and reliable diagnosis support for hospitals, physicians, and other healthcare facilities across the country. We offer an MSI Study (Microsatellite Instability) IHC test in Dakor  with timely reports. This test is performed by our experienced hematopathologists with the utmost care. 

What makes Sterling Accuris a better pathology lab than others?

For us, precision care, safe sample collection, timely delivery of reports, and precise reporting of patient results while adhering to health and safety precautions are the cornerstone of our success.

What other packages does Sterling Accuris offer?

Sterling Accuris offers a range of packages including Senior citizen (male and female) package, healthy heart profile, diabetes profile, vitamin profile, covid immunity package and much more. Visit our website to learn more about these packages.

Do you provide home visit/collection service?

Yes. We do provide home collection services at your doorstep.

Please go ahead and book your visit today from our top menu options in this website / chat or do call us on 812 813 0000.

Is there any preparation or precautions for patient before tests or body checkup?

Fasting maybe required in case of a few tests to ensure accurate results. 

In general, it is also advisable to abstain from alcohol and heavy diet at least for 24 hours before any health test. You can see the requirement for each test on the product page on our website / app.

How long does it take to receive test results?

Though most tests are completed and reported within about 24 hours of receiving the sample for testing, certain tests take several days to weeks.

Your soft copy will be sent on registered email id and Whatsapp. Also, you will receive SMS with link to download your report. Also, your report is available on our website / app.

To know the status of the report, you can call our customer care team on 812 813 0000.

MSI Study (Microsatellite Instability) IHC test in Dakor

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Sterling Accuris offers the MSI Study (Micro Satellite Instability) IHC Test in Dakor   to screen for Lynch syndrome. 

Overview of the MSI Study (Microsatellite Instability) IHC Test  

In this test, tumour-specific microsatellite instability is tested. Microsatellites are repeated DNA stretches that are dispersed across the human genome. When alteration in these repetitive DNA segments occurs due to DNA mismatch repair, this results in microsatellite instability. A major contributor to carcinogenesis is impaired DNA mismatch repair, which can occur randomly, or as a result of Lynch syndrome, also called hereditary non-polyposis colorectal cancer (HNPCC).  Studies have shown that solid tumours in advanced stages with DNA mismatch repair defects (MSI-H) are more likely to respond to immunotherapies.

The MSI Study (Microsatellite Instability) IHC test can be valuable for clinical decision-making. Sterling Accuris offers a reliable MSI Study (Microsatellite Instability) IHC test in Dakor with timely reports.

Why and When is an MSI Study (Microsatellite Instability) IHC Test Done? 

MSI Study (Micro Satellite Instability) IHC test is an important tumor screening test for newly diagnosed colorectal cancer to identify Lynch syndrome. 

The signs of Lynch syndrome the leading contributor to hereditary colorectal cancer is:

  • Blood in stool
  • Unexplained diarrhoea 
  • Cramps in the abdomen
  • Chronic constipation
  • Decrease in stool size
  • Bloating and gas
  • Unexplained weight loss
  • Tiredness
  • Vomiting  

Sterling Accuris Ahmedabad offers a reliable MSI Study (Microsatellite Instability) IHC test in Dakor.

MSI Study (Microsatellite Instability) IHC Test: Main Highlights

  • Instructions: Fasting is not required
  • Recommended Age: All age groups
  • Sample type for test: Paraffin tissue block

How to Interpret the MSI Study (Microsatellite Instability) IHC Test Report

Interpretation of the results for the MSI Study (Microsatellite Instability) IHC test in adult females and males are given in the table:

Parameter

Range 

MSI Study (Microsatellite Instability) IHC

MSI high - 2 or more out of 5 core markers showing instability - the probability of Lynch syndrome is high

MSI low - 1 out of 5 core markers showing instability cannot determine the probability of Lynch syndrome

MSI stable - 0 out of 5 core markers showing instability - no chance of Lynch syndrome

Causative factors:

  • Mutation in the genes of mismatch repair
  • Hereditary conditions

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