Immunophenotyping For ALPS in Godhra
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Immunophenotyping For Alps1
FAQ
What other tests can diagnose ALPS?
Other tests for ALPS include:
- Checking the existence of alpha beta double-negative T (DNT) cells in blood and tissue samples
- Checking for the elevation of cytokine IL 10, IL 18, and Fas Ligand
- In –vitro analysis of Fas-mediated apoptosis
What is a lymphocyte?
Lymphocytes are white blood cells that play an important part in our immune system. They allow you to fight against infection and diseases and thus are also called immune cells. There are two types of lymphocytes – T cells/lymphocytes and B cells/lymphocytes. The T cells directly act on the infected cells/tumor cells/abnormal cells in the body and kill them. B cells produce antibodies against the infecting organism/or any foreign material found in the body
Why should you book the Immunophenotyping for ALPS Test with Sterling Accuris?
Sterling Diagnostics uses the best facilities to provide accurate results. Book an Immunophenotyping for ALPS Test in Godhra with us for timely results.
What are the other types of lymphoproliferative diseases?
Lymphoproliferative diseases are a group of diseases that occur due to unregulated production of lymphocytes. Immunocompromised individuals are affected by this disease. Different types of lymphoproliferative diseases include common variable immunodeficiency (CVID), severe combined immunodeficiency (SCID), Wiskott-Aldrich syndrome, ataxia-telangiectasia, ALPS, and a few more.
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For us, precision care, safe sample collection, timely delivery of reports, and precise reporting of patient results while adhering to health and safety precautions are the cornerstone of our success.
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Yes. We do provide home collection services at your doorstep.
Please go ahead and book your visit today from our top menu options in this website / chat or do call us on 812 813 0000.
How long does it take to receive test results?
Though most tests are completed and reported within about 24 hours of receiving the sample for testing, certain tests take several days to weeks.
Your soft copy will be sent on registered email id and Whatsapp. Also, you will receive SMS with link to download your report. Also, your report is available on our website / app.
To know the status of the report, you can call our customer care team on 812 813 0000.
Is there any preparation or precautions for patient before tests or body checkup?
Fasting maybe required in case of a few tests to ensure accurate results.
In general, it is also advisable to abstain from alcohol and heavy diet at least for 24 hours before any health test. You can see the requirement for each test on the product page on our website / app.
Immunophenotyping for ALPS Test in Godhra
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Sterling Accuris Diagnostics offers the Immunophenotyping for ALPS Test in Godhra to detect a deregulated immune system.
Overview of ALPS Test (Autoimmune lymphoproliferative syndrome test)
The ALPS Test is performed when the immune system gets deregulated and as a result, several lymphoproliferative diseases occur. ALPS is a genetic disorder where lymphocyte homeostasis is disturbed due to defective cellular apoptosis (An auto-programmed cell-death mechanism). The lymphocytes/white blood cells grow more than required and accumulate in lymph nodes, liver, and spleen. This accumulation causes the enlargement of these organs. This disturbed lymphocyte homeostasis results in an increased tendency towards lymphoma and autoimmune diseases.
Detect the presence of ALPS disorders by booking an Immunophenotyping for ALPS Test near you. Sterling Accuris offers an accurate Immunophenotyping for ALPS Test in Godhra, with timely reports.
Why And When Is An Immunophenotyping For ALPS Test Done?
The Immunophenotyping for ALPS Test is done to identify this disease. In fact, ALPS is a type of lymphoproliferative disorder with mutations in the Fas receptor of lymphocytes. These receptors help to facilitate the apoptosis of lymphocytes and prevent their unnecessary accumulation. The symptoms are visible in the first year of life with manifestations like non-infectious, non-malignant lymphoid expansion. The malignant form of lymphoma occurs at a very late stage. This disease is more common in males as compared to females.
A doctor may recommend Immunophenotyping for ALPS Test when a person shows the following symptoms:
- Increased size of lymph nodes/lymphadenopathy
- Increased size of spleen/splenomegaly
- Enlarged liver/hepatomegaly
- Autoimmune cytopenia that includes neutropenia, thrombocytopenia, and hemolytic anemia
Immunophenotyping for ALPS Test: Main Highlights
- Instructions: Fasting is not required
- Recommended age group: All age groups
- Sample type: Blood sample in EDTA tube
How to Interpret the Immunophenotyping for ALPS Test Report
The result of an Immunophenotyping for an ALPS Test should be in the following cutoff range:
T-cell receptor alpha beta positive and CD4- CD8 double negative cells:
Test | Cutoff Range |
Of total lymphocytes | > 1.5 % |
Of CD3 + lymphocytes | > 2.5 % |
Correlation with other data is required for a proper diagnosis. This includes checking for lymphadenopathy, phenomenally, lymphocyte apoptosis, and many other factors.
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