Centromere Antibody in Indore

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Centromere Antibody ELISA
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  • Centromere Antibody ELISA1Centromere Antibody ELISA

FAQ

Why book the Centromere Antibody test with Sterling Accuris?

Sterling Accuris offers a Centromere Antibody Test in Indore . Our healthcare team provides a safe home collection service for the Centromere Antibody test at your convenience.

Who is tested for centromere antibodies?

Usually, only individuals experiencing CREST symptoms undergo testing for CA. Nonetheless, some individuals may test positive for ACA before these symptoms arise, and ACA testing may also be conducted alongside testing for other autoimmune disorders like ANA testing.

What are the types of systemic sclerosis?

Systemic sclerosis has 2 subtypes namely:

  • Diffuse cutaneous systemic sclerosis (affects the whole body)
  • Limited cutaneous systemic sclerosis (one or more symptoms collectively called CREST syndrome)

What are the symptoms of CREST Syndrome?

The symptoms of CREST syndrome include:

  • Calcinosis: Deposits of calcium under the skin
  • Raynaud phenomenon: Less blood flow to fingers and toes resulting in them turning white and blue
  • Esophageal dysfunction: Trouble swallowing, acid reflux, and heartburn
  • Sclerodactyly: The skin of fingers are tight, thick and shiny

What other packages does Sterling Accuris offer?

Sterling Accuris offers a range of packages including Senior citizen (male and female) package, healthy heart profile, diabetes profile, vitamin profile, covid immunity package and much more. Visit our website to learn more about these packages.

What makes Sterling Accuris a better pathology lab than others?

For us, precision care, safe sample collection, timely delivery of reports, and precise reporting of patient results while adhering to health and safety precautions are the cornerstone of our success.

Do you provide home visit/collection service?

Yes. We do provide home collection services at your doorstep.

Please go ahead and book your visit today from our top menu options in this website / chat or do call us on 812 813 0000.

How long does it take to receive test results?

Though most tests are completed and reported within about 24 hours of receiving the sample for testing, certain tests take several days to weeks.

Your soft copy will be sent on registered email id and Whatsapp. Also, you will receive SMS with link to download your report. Also, your report is available on our website / app.

To know the status of the report, you can call our customer care team on 812 813 0000.

Is there any preparation or precautions for patient before tests or body checkup?

Fasting maybe required in case of a few tests to ensure accurate results. 

In general, it is also advisable to abstain from alcohol and heavy diet at least for 24 hours before any health test. You can see the requirement for each test on the product page on our website / app.

Centromere Antibody Test in Indore

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Sterling Accuris offers the Centromere Antibody Test in Indore, for the diagnosis of systemic sclerosis (SSc), and to distinguish it from other autoimmune conditions. 

Overview of the Centromere Antibody Test

The Centromere Antibody test is a blood test that helps evaluate certain autoimmune diseases, mainly systemic sclerosis. This test measures the presence of antibodies in the blood that target the centromere proteins, essential chromosome components. This test is also known as the CENP antibody test. 

Sterling Accuris Diagnostics offers an accurate Centromere Antibody Test in Indore  with timely reports.

Why And When Is The Centromere Antibody Test Done?

The Centromere Antibody Test is an essential diagnostic tool that checks for antibodies against centromeres, proteins that help separate chromosomes during cell division.

A doctor may recommend a Centromere Antibody test in case a person exhibits symptoms that include: 

  • Raynaud's phenomenon (fingers and toes turning white or blue in response to cold or stress)
  • Skin thickening or hardening
  • Dysphagia (difficulty swallowing)
  • Gastrointestinal issues (acid reflux, bloating, and constipation)
  • Shortness of breath 

This test is also recommended in the following cases:

  • Detecting minimal scleroderma
  • Checking of limited scleroderma progression
  • Assess pulmonary arterial hypertension risk

Centromere Antibody Test: Main Highlights

Instructions: No fasting required

Recommended Age: All age groups

Sample Type: Blood sample in a plain (serum) tube

How to Interpret the Centromere Antibody Test Report

The table below shows the different levels and their parameters in individuals of all ages, including standard and elevated/low levels:

Parameters

Normal range

Mild autoimmune disease

Severe autoimmune disease

Centromere Antibody Levels

Less than 1:40

1:40 to 1:80

Higher than 1:80


If your test shows positive results, indicating the presence of anti-centromere antibodies in your blood, and you also experience symptoms of CREST, it is highly probable that you have limited cutaneous scleroderma, a type of systemic scleroderma. 

On the other hand, if your test shows negative results, it is likely that your symptoms are caused by a different condition. However, it is important to note that although rare, it is still possible to have limited cutaneous scleroderma without producing anti-centromere antibodies, leading to a negative result.

The following reasons for abnormal centromere antibody levels are listed below:

  • Systemic sclerosis
  • Limited scleroderma
  • Other autoimmune diseases like Systemic lupus erythematosus (SLE) and Rheumatoid Arthritis
  • Age and gender

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