Chromosome 17p deletion in Mahuva
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Age Group 05-90 years
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The change that occurs at the DNA/genetic level is called cytogenetic abnormality. Cytogenetics utilises advanced laboratory techniques to identify small changes in chromosomes that contain genes. Any chromosomal abnormalities like broken, missing, rearranged, or extra chromosomes can be detected by cytogenetic techniques. Some common cytogenetic abnormality-associated diseases are multiple myeloma, Down’s syndrome, chronic lymphocytic leukaemia etc.
Multiple myeloma is one of the most common cancers of B-cells in blood that arises due to chromosome 17p deletion. The gene involved is TP53 that is one most important risk factor for this disease. The disease characterised by:
Besides the traditional chromosome G-banding technique, there are many advanced molecular diagnostic tests available for testing genetic changes at pre-natal stage like: Fluorescent InSitu Hybridization, Chromosomal Microarray, SNP analysis, PCR for DNA fragment size analysis, etc.
Sterling Diagnostics uses the best facilities to provide accurate results. Book Chromosome 17p deletion - FISH Test in Mahuva with us for timely results.
For us, precision care, safe sample collection, timely delivery of reports, and precise reporting of patient results while adhering to health and safety precautions are the cornerstone of our success.
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Though most tests are completed and reported within about 24 hours of receiving the sample for testing, certain tests take several days to weeks.
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Fasting maybe required in case of a few tests to ensure accurate results.
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Sterling Accuris Diagnostics offers the Chromosome 17p deletion - FISH Test in Mahuva to detect cytogenetic abnormalities on chromosome 17 and related disease like chronic lymphocytic leukaemia.
The Chromosome 17p deletion - FISH Test is performed to detect the loss of DNA segments from the short arm of chromosome 17. Chromosome 17 contains the code for the TP53 gene, a tumour suppressor gene. It is involved in diverse cellular processes and plays an essential role in cell division and in damaged DNA repair. The deletion in chromosome 17p can result in severe diseases like multiple myeloma, chronic lymphocytic leukaemia (CLL), acute lymphocytic leukaemia, etc.
Sterling Accuris Diagnostics offers an accurate Chromosome 17p deletion - FISH Test in Mahuva.
The Chromosome 17p deletion - FISH Test is a frequent event in several malignancies like leukaemia, myeloma, etc. This test is done at both the pre-natal and post-natal stage. At pre-natal stage, it is particularly referred for high risk conditions, and at the post-natal stage to detect the reasons for developmental delays.
A doctor may recommend the test when a person shows following the symptoms:
Pre-natal stage:
Postnatal stage:
The Chromosome 17p deletion - FISH Test is done with a technique called Fluorescent InSitu Hybridization (FISH). In this technique fluorescently labelled probes bind with single stranded sample DNA/RNA. The samples are then subjected for fluorescence microscopic analysis to identify the deletion chromosome 17p region.
The fluorescent intensity after is read as output given as:
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Pre Instructions
Recommended by Health Experts
NABL Accredited Labs
Age Group 05-90 years
Recommended for Men, Women
Lab test Booked
Satisfied Customers
Collection Centre & Labs
Cities we are present in
Our Presence
Pathology lab in Adipur
Pathology lab in Ahmedabad
Pathology lab in Balotra
Pathology lab in Bhavnagar
Pathology lab in Bhuj
Pathology lab in Botad
Pathology lab in Dakor
Pathology lab in Deesa
Pathology lab in Gandhidham
Pathology lab in Gandhinagar
Pathology lab in Godhra
Pathology lab in Halol
Pathology lab in Himmatnagar
Pathology lab in Indore
Pathology lab in Jaipur
Pathology lab in Jamnagar
Pathology lab in Jodhpur
Pathology lab in Kadi
Pathology lab in Kalol
Pathology lab in Khambhat
Pathology lab in Kudasan
Pathology lab in Lunavada
Pathology lab in Mahuva
Pathology lab in Mansa
Pathology lab in Mehsana
Pathology lab in Modasa
Pathology lab in Nadiad
Pathology lab in Navsari
Pathology lab in Palanpur
Pathology lab in Patan
Pathology lab in Petlad
Pathology lab in Rajkot
Pathology lab in Ratlam
Pathology lab in Sanand
Pathology lab in Surat
Pathology lab in Udaipur
Pathology lab in Una
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