PML/RARA by FISH in Mahuva
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Pml/Rara1
FAQ
What is the RARA gene?
The RARA gene encodes the retinoic acid receptor, alpha (RARα) protein, which regulates gene transcription to drive the maturation of immature white blood cells beyond the promyelocyte phase.
Where is the PML gene located?
The PML gene is located on the long arm of chromosome 15 at 15q22.
Why should I book a PML/RARA FISH test with Sterling Accuris?
At Sterling Diagnostics, our team of expert pathologists work in meticulously designed facilities to offer results that are both precise and dependable. Book a PML/RARA FISH test in Mahuva with us for timely results.
Is PML an oncogene (genes that transform cells into tumors)?
PML is not an oncogene, but it is a tumor suppressor.
What other packages does Sterling Accuris offer?
Sterling Accuris offers a range of packages including Senior citizen (male and female) package, healthy heart profile, diabetes profile, vitamin profile, covid immunity package and much more. Visit our website to learn more about these packages.
What makes Sterling Accuris a better pathology lab than others?
For us, precision care, safe sample collection, timely delivery of reports, and precise reporting of patient results while adhering to health and safety precautions are the cornerstone of our success.
Do you provide home visit/collection service?
Yes. We do provide home collection services at your doorstep.
Please go ahead and book your visit today from our top menu options in this website / chat or do call us on 812 813 0000.
How long does it take to receive test results?
Though most tests are completed and reported within about 24 hours of receiving the sample for testing, certain tests take several days to weeks.
Your soft copy will be sent on registered email id and Whatsapp. Also, you will receive SMS with link to download your report. Also, your report is available on our website / app.
To know the status of the report, you can call our customer care team on 812 813 0000.
Is there any preparation or precautions for patient before tests or body checkup?
Fasting maybe required in case of a few tests to ensure accurate results.
In general, it is also advisable to abstain from alcohol and heavy diet at least for 24 hours before any health test. You can see the requirement for each test on the product page on our website / app.
PML/RARA FISH Test in Mahuva
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Sterling Accuris Diagnostics offers the PML/RARA FISH test in Mahuva to identify any abnormalities indicating a PML/RARA fusion.
Overview of PML/RARA FISH Test
The PML/RARA FISH test is a laboratory testing method used to detect the presence of an abnormal fusion gene associated with two types of leukemia: acute promyelocytic leukemia (APL) and acute myeloid leukemia (AML). It specifically detects the fusion gene PML/RARA, which is responsible for the development of APL and certain types of AML. The test utilizes fluorescently labeled probes that bind to regions of the gene-specific to PML/RARA. The test is a prognostic tool for predicting disease progression in APL.
Book a PML/RARA FISH test near you to diagnose certain types of leukemia and other diseases associated with PML/RARA fusion. Sterling Accuris offers a reliable PML/RARA FISH test in Mahuva with timely reports.
Why and When is the PML/RARA FISH Test Done
Acute Promyelocytic Leukemia (APL) is associated with life-threatening clotting disorders, due to an overproduction of clotting factors. Common complications can include intracranial hemorrhage, deep vein thrombosis (blood clots), and pulmonary embolism (blood clots in the lungs). Acute myeloid leukemia (AML) complications can include infections, anemia, and bleeding due to low platelet count. AML can also affect other organs, such as the heart, kidneys, or lungs, and can cause other life-threatening complications. Therefore, it is important to have these tests done as soon as possible to prevent any further damage. Sterling Accuris Diagnostics offers a sensitive PML/RARA FISH test in Mahuva.
The doctor may recommend this test if a person exhibits symptoms like:
- Unexplained fever
- Extreme fatigue
- Weight loss
- Night sweats
- Enlarged lymph nodes
- Joint pain
- Shortness of breath
- Loss of appetite
- Abnormal infections
- Headache
- Visual disturbances
- Seizures
PML/RARA FISH Test: Main Highlights
- Instructions: No fasting is required
- Recommended age: All age groups
- Sample type for test: Blood sample in plain (serum) tube
How to Interpret the PML/RARA FISH Test Report
A positive result on a FISH test for a PML/RARA gene rearrangement indicates that the leukemia cells have a certain genetic abnormality. This implies that the person has a higher risk of developing acute promyelocytic leukemia (APL) than the general population.
A negative result on a FISH test for a PML/RARA gene rearrangement indicates that the leukemia cells do not have the genetic abnormality that is linked to APL.
Causative Factors
- Exposure to highly active antiretroviral therapy
- Exposure to arsenic or heavy metals
- Severely compromised immunity due to high levels of infection, cancer, or leukemia
- Previous treatment with chemotherapy agents such as vincristine or cytarabine
- Exposure to radiation therapy
- Family history
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