Immunophenotyping For Leukocyte Adhesion Defect (LAD) -I in Mehsana
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Pre Instructions
Recommended by Health Experts
NABL Accredited Labs
Age Group 05-90 years
Recommended for Men, Women
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Immunophenotyping For Leukocyte Adhesion Defect -I1
FAQ
What is immunophenotyping?
A test that identifies cells based on the types of antigens and markers present on their surface. Antibodies are used for the identification of cell antigens.
Why should you book an Immunophenotyping for Leukocyte Adhesion Defect (LAD)-1 test with Sterling Accuris?
Sterling Accuris specializes in providing reliable diagnosis support for physicians and healthcare facilities across the country. We offer an Immunophenotyping for Leukocyte Adhesion Defect (LAD)-1 test in Mehsana with timely reports. We also offer safe home collections when required.
How are abnormal results reported in LAD 1 immunophenotyping?
People with LAD 1 Surface markers- CD11a, CD11b, and CD18 were found to be marked reduced on the surface of neutrophils.
How is LAD 1 inherited?
The inheritance of this condition follows an autosomal recessive pattern, wherein both copies of the gene in every cell carry mutations. Although the parents of an individual with this autosomal recessive condition possess one copy of the mutated gene, they typically do not exhibit symptoms of the disorder.
What other packages does Sterling Accuris offer?
Sterling Accuris offers a range of packages including Senior citizen (male and female) package, healthy heart profile, diabetes profile, vitamin profile, covid immunity package and much more. Visit our website to learn more about these packages.
What makes Sterling Accuris a better pathology lab than others?
For us, precision care, safe sample collection, timely delivery of reports, and precise reporting of patient results while adhering to health and safety precautions are the cornerstone of our success.
Do you provide home visit/collection service?
Yes. We do provide home collection services at your doorstep.
Please go ahead and book your visit today from our top menu options in this website / chat or do call us on 812 813 0000.
How long does it take to receive test results?
Though most tests are completed and reported within about 24 hours of receiving the sample for testing, certain tests take several days to weeks.
Your soft copy will be sent on registered email id and Whatsapp. Also, you will receive SMS with link to download your report. Also, your report is available on our website / app.
To know the status of the report, you can call our customer care team on 812 813 0000.
Is there any preparation or precautions for patient before tests or body checkup?
Fasting maybe required in case of a few tests to ensure accurate results.
In general, it is also advisable to abstain from alcohol and heavy diet at least for 24 hours before any health test. You can see the requirement for each test on the product page on our website / app.
Immunophenotyping for Leukocyte Adhesion Defect (LAD)-1 test in Mehsana
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Sterling Accuris offers an Immunophenotyping for Leukocyte Adhesion Defect (LAD)-1 Test in Mehsana to help diagnose leukocyte adhesion deficiency syndrome-1 in people with immunodeficiency.
Overview of the Immunophenotyping for Leukocyte Adhesion Defect (LAD)-1 Test
Leukocyte Adhesion defect is an autosomal recessive disorder, typically seen in infants or early childhood. Leukocyte adhesion defect results in immune dysfunction where the immune system of the body is not able to protect the body against pathogens. Mutation in the Integrin beta-2 (ITGB2) gene results in LAD 1 defect. An important component of the beta 2 subunit (CD18) required for the expression of the surface antigens- CD11a/CD18, CD11b/CD18, and CD11c/CD18 is made by this gene. Therefore, defects in LAD1 lead to decreased expression of these proteins on the surface of immune cells.
The Immunophenotyping for Leukocyte Adhesion Defect (LAD)-1 test can provide important clues about the cause of immunodeficiency in people, which is helpful for clinicians in planning treatment. Book an Immunophenotyping for Leukocyte Adhesion Defect (LAD)-1 test near you for accurate results.
Why and When is an Immunophenotyping for Leukocyte Adhesion Defect (LAD)-1 Test done?
People with LAD 1 defect develop severe bacterial and fungal infections. The doctor might suggest this test for the following conditions:
- Detachment of the umbilical cord stump takes more than 2 weeks after birth in newborns.
- Inflammation/infection of the umbilical cord occurs.
A person may require this test if the following signs and symptoms of LAD-1 deficiency may be present:
- Leukocytosis (elevated white blood cells) in complete blood count
- Bacterial/fungal infection of the nose and mouth
- Inflammation of gums
- No pus form at the site of infection
- Wounds that heal slowly
Immunophenotyping for Leukocyte Adhesion Defect (LAD)-1 Test: Main Highlights
- Instructions: Fasting is not required
- Recommended Age: Primarily 18 years or younger
- Sample type for test: Blood sample in EDTA tube
Causative factors:
- Abnormal Immunophenotyping for Leukocyte Adhesion Defect (LAD)-1 levels can be caused by an autosomal recessive genetic disorder.
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