TPMT Genotyping By Sanger in Mehsana

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TPMT Genotyping-Sanger

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Sterling Accuris Pathology reports are often used to diagnose diseases, and determine the extent or stage of the disease. The report usually includes information about the patient, the specimen, the diagnostic tests that were performed, and the pathologist's interpretation of the results.

The turnaround time for a pathology report is typically calculated from the time the specimen is received by the laboratory to the time the report is finalized and delivered. The specific steps involved in the process can vary depending on the laboratory and the type of specimen being analyzed.

The time required for examination, processing, diagnosis, and reporting can vary depending on the complexity of the tests or case, the workload of the laboratory, and other factors.

*The total turnaround time for a pathology report can range from a few hours to several days, depending on the urgency of the case and the policies of the laboratory.

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FAQ

What makes Sterling Accuris a better pathology lab than others?

For us, precision care, safe sample collection, timely delivery of reports, and precise reporting of patient results while adhering to health and safety precautions are the cornerstone of our success.

What other packages does Sterling Accuris offer?

Sterling Accuris offers a range of packages including Senior citizen (male and female) package, healthy heart profile, diabetes profile, vitamin profile, covid immunity package and much more. Visit our website to learn more about these packages.

Do you provide home visit/collection service?

Yes. We do provide home collection services at your doorstep.

Please go ahead and book your visit today from our top menu options in this website / chat or do call us on 812 813 0000.

Is there any preparation or precautions for patient before tests or body checkup?

Fasting maybe required in case of a few tests to ensure accurate results.

In general, it is also advisable to abstain from alcohol and heavy diet at least for 24 hours before any health test. You can see the requirement for each test on the product page on our website / app.

How long does it take to receive test results?

Though most tests are completed and reported within about 24 hours of receiving the sample for testing, certain tests take several days to weeks.

Your soft copy will be sent on registered email id and Whatsapp. Also, you will receive SMS with link to download your report. Also, your report is available on our website / app.

To know the status of the report, you can call our customer care team on 812 813 0000.

TPMT Genotyping by Sanger Sequencing in Mehsana

Sterling Accuris Diagnostics offers TPMT Genotyping by Sanger Sequencing in Mehsana. This test is pivotal for patients who are about to begin treatment with thiopurine drugs, commonly used in conditions such as leukaemia, inflammatory bowel disease, and autoimmune disorders.

TPMT genotyping identifies genetic variants in the thiopurine methyltransferase (TPMT) gene that affect how an individual processes specific medications, particularly thiopurines like azathioprine, mercaptopurine, and thioguanine. They are commonly prescribed for certain autoimmune disorders and cancers. Thiopurine S-methyltransferase (TPMT) deficiency means the body has less enzyme needed to break down thiopurine medications.

The TPMT Genotyping by Sanger Sequencing in Mehsana is crucial for determining appropriate dosages of these drugs to reduce the risk of adverse effects. More than 23 variants in the TPMT gene have been identified that are associated with decreased TPMT activity. The most significant variants influencing drug metabolism are TPMT2, TPMT3A, and TPMT3C. Doctors recommend this test before beginning thiopurine medication, although it can also be done in those already undergoing treatment.

Key Details of the Test:

Preparation: No special preparation is needed.
Prescription: Requires a doctor's prescription.
Sample Required: A blood sample is taken (EDTA Tube).
Turnaround Time: Results are typically available within a few weeks.

Why is Sanger Sequencing ideal for TPMT Genotyping?

Sanger sequencing is highly accurate for pinpointing particular changes in the TPMT gene, which is essential for adjusting drug doses safely based on a person's genetic makeup. It's particularly suitable for examining small DNA areas and effectively detecting uncommon TPMT variants that could affect medication response and toxicity.

FAQs

Who should get the TPMT genotyping test?

Individuals who are considering or currently taking thiopurine medications should be tested to ensure proper dosing.

What might a TPMT test reveal?

The test can reveal if you have a mutation that could lead to slower drug metabolism, indicating a risk for adverse drug reactions.

How can TPMT genotyping influence treatment decisions?

Based on the results, healthcare providers can adjust thiopurine drug dosages or consider alternative treatments.

Can I take thiopurine drugs if I have a TPMT mutation?

Yes, but your doctor may prescribe a lower dose and monitor you closely for side effects.

For the convenience of those needing TPMT Genotyping by Sanger Sequencing in Mehsana, Sterling Accuris Diagnostics offers a home visit sample collection. Contact our NABL-accredited lab for fast and seamless services and book a home collection, ensuring a hassle-free testing process.