Best Pathology Lab in India for Blood Test & Full Body Checkup Test Slash Chromosomal Microarray (CMA)-315k-aCGH in Petlad

Chromosomal Microarray (CMA)-315k-aCGH in Petlad

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Chromosomal Microarray 315k, PoC, Maternal Cell Contamination (MCC)
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FAQ

What is aneuploidy?

The imbalance in the number of chromosomes is called aneuploidy. Humans have a defined set of chromosomes that is two sets of 23 chromosomes represented as 2n (Diploid). If this number gets altered due to duplication/deletion, this can cause aneuploidy leading to severe disorders depending upon the affected chromosomal locus.  

What distinguishes the karyotype from the CMA?

In contrast to CMA, which can employ uncultured amniocytes, karyotype analysis needs a manual selection of cultured cells. 

What is Down’s syndrome?

Down’s syndrome is the duplication of chromosomes occurring at number 21, called trisomy 21.  It shows many symptoms that include dysmorphic features (e.g., atypically small head or flat face); small white/grey spots on the edge of the iris; cardiovascular problems; gastrointestinal problems; neuromuscular problems.

Why should I book Chromosomal Microarray 315 (CMA 315k) with POC Karyotype Test with Sterling Accuris Diagnostics?

Sterling Accuris Diagnostics is at the forefront of pathology services in India, with international quality standards. Our NABL-accredited laboratory specializes in providing quick and reliable primary diagnosis support for hospitals, physicians and other healthcare facilities across the country. 

It is extremely convenient to book a Chromosomal Microarray 315 (CMA 315k) with POC Karyotype Test with us which would give you accurate and precise results at a great price.

Is Down syndrome tested for using microarrays?

Common chromosome disorders like Down syndrome can be found via microarray testing, as can chromosome disorders that a karyotype would not reveal.

What are micro-level chromosomal abnormalities?

Micro-level chromosomal abnormalities represent very small changes in chromosomes that cause abnormal cell division like deletion, duplication, inversion, and translocation.

What makes Sterling Accuris a better pathology lab than others?

For us, precision care, safe sample collection, timely delivery of reports, and precise reporting of patient results while adhering to health and safety precautions are the cornerstone of our success.

What other packages does Sterling Accuris offer?

Sterling Accuris offers a range of packages including Senior citizen (male and female) package, healthy heart profile, diabetes profile, vitamin profile, covid immunity package and much more. Visit our website to learn more about these packages.

Do you provide home visit/collection service?

Yes. We do provide home collection services at your doorstep.

Please go ahead and book your visit today from our top menu options in this website / chat or do call us on 812 813 0000.

How long does it take to receive test results?

Though most tests are completed and reported within about 24 hours of receiving the sample for testing, certain tests take several days to weeks.

Your soft copy will be sent on registered email id and Whatsapp. Also, you will receive SMS with link to download your report. Also, your report is available on our website / app.

To know the status of the report, you can call our customer care team on 812 813 0000.

Is there any preparation or precautions for patient before tests or body checkup?

Fasting maybe required in case of a few tests to ensure accurate results. 

In general, it is also advisable to abstain from alcohol and heavy diet at least for 24 hours before any health test. You can see the requirement for each test on the product page on our website / app.

Chromosomal Microarray (CMA)-315k-aCGH Test in Petlad

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Sterling Accuris Diagnostics offers the Chromosomal Microarray (CMA)-315k-aCGH Test in Petlad to detect major chromosomal imbalances, particularly in unborn babies.    

Overview of Chromosomal Microarray -315k-aCGH Test

The Chromosomal Microarray (CMA)-315k-aCGH Test is performed in both prenatal and postnatal settings to detect any major chromosomal abnormalities like aneuploidy. CMA with 315k-aCGH, is an advanced molecular genetic testing that can identify submicroscopic chromosomal changes. This test is used to identify chromosomal trisomy and monosomy in a foetus, which can lead to severe diseases like Down’s syndrome and Turner’s syndrome respectively; and many more micro-changes in chromosomes.       

Why And When Is A CMA-315k-aCGH Test Done?

The Chromosomal Microarray (CMA)-315k-aCGH Test is done to identify micro-level chromosomal abnormalities in a foetus. This technique offers an additional advantage over the traditional chromosomal karyotyping/G Banding technique for chromosomal changes, which in turn leads to a more effective diagnosis.

A doctor may recommend the Chromosomal Microarray-315k-aCGH Test when someone shows the following symptoms: 

In the prenatal stage:

  • More than 40 years of the pregnant women
  • One or more past miscarriage
  • Foetal anomalies detected by ultrasound
  • Anxiety during pregnancy
  • High chances of chromosomal abnormalities based on blood test

 In the postnatal stage:

  • Developmental delays
  • Intellectual disabilities
  • Symptoms of Autism Spectrum Disorders (ASD)
  • Multiple Congenital Anomalies (MCA)

Chromosomal Microarray (CMA)-315k-aCGH Test: Main Highlights

  • Instructions: Fasting is not required
  • Recommended age group: All age groups
  • Sample type: Blood in EDTA tube, Amniotic Fluid, POC, Cordocentesis: A method used to collect a sample of the fetus's blood from the umbilical cord for further testing.

How to interpret the CMA-315k-aCGH Test Report

The Chromosomal Microarray (CMA)-315k-aCGH Test is done by hybridising fluorescently labelled DNA from the sample and control DNA onto an array containing multiple probes from representative sequences from all over the human genome. The results are read after complementary binding of DNA samples with the probe as fluorescent intensity by using imaging software. Finally, the ratio of fluorescent intensity after normalisation is read as output given:

  • If the ratio is 1 that indicates equal hybridization/contribution from the patient and control sample which in turn represents a normal copy number at a particular locus
  • If the ratio is significantly greater than 1 indicates that more of the patient’s DNA hybridised at a particular location compared to the control DNA this could be due to chromosomal duplication or trisomy
  • If the ratio is significantly less than 1 indicates more hybridization of the control DNA sequences compared to the patient’s DNA this could be due to chromosomal deletion or monosomy.  

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