HAMS Test-PNH Work Up in Petlad

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HAMS Test-PNH Work Up
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Sterling Accuris offers a range of packages including Senior citizen (male and female) package, healthy heart profile, diabetes profile, vitamin profile, covid immunity package and much more. Visit our website to learn more about these packages.

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How long does it take to receive test results?

Though most tests are completed and reported within about 24 hours of receiving the sample for testing, certain tests take several days to weeks.

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Is there any preparation or precautions for patient before tests or body checkup?

Fasting maybe required in case of a few tests to ensure accurate results. 

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HAM's Test-PNH Workup in Petlad

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Sterling Accuris Diagnostics offers the HAM's Test-PNH Workup in Petlad to diagnose Paroxysmal nocturnal hemoglobinuria (PNH).

Overview of the HAM's Test-PNH Workup

The HAM's Test-PNH Workup is done to detect certain acquired and congenital blood disorders and Paroxysmal Nocturnal Hemoglobinuria (PNH). PNH is a rare disease with a variety of clinical manifestations which include hemolytic anemia and hemoglobinuria, the most common form.

The term comes from:

  • Paroxysmal refers to a sudden and irregular occurrence.

  • Nocturnal means that the phenomenon takes place at night.

  • Hemoglobinuria describes the presence of hemoglobin in urine, which turns it dark in color.

This disorder occurs because of a genetic mutation in the phosphatidylinositol glycan class A (PIGA) gene of hematopoietic stem cells. This in turn results in a deficiency in the glycosylphosphatidylinositol (GPI) protein, which is required for attaching other protein moieties on red blood cell’s (RBC’s) surface. The disease PNH is rare but when present, it can considerably affect the quality of life of the person.

Sterling Accuris Diagnostics offers a reliable HAM's Test-PNH Workup in Petlad with timely reports.

Why And When Is A HAM's Test-PNH Workup Done?

The HAM's Test-PNH WorkUp identifies PNH and its various clinical manifestations.

A doctor may recommend this workup in the following cases:

  • Hemolytic anemia

      • Weakness

      • Blood in urine

      • Dizziness

      • Hepatomegaly

      • Splenomegaly

  • Thrombosis

  • Bone marrow failure

  • Smooth muscle dystonia

  • Renal insufficiency

  • Fatigue

  • Shortness of breath

HAM's Test-PNH Workup: Main Highlights

  • Instructions: Fasting not required

  • Recommended age group: All age groups

  • Sample type: Blood sample in EDTA tube

How to interpret the HAM's Test-PNH Workup Report

The HAM's Test-PNH WorkUp is done using a blood sample.

  • A normal HAM's test result is exhibited by RBCs that don’t become fragile in a specific acid solution. A positive report would result in the RBCs becoming fragile, indicating PNH.

  • If PNH workup is normal when CD59 (MIRL), a glycoprotein, and CD55 (DAF) are present. If abnormal, the absence or reduced expression of both CD59 and CD55 on RBCs is diagnostic of PNH.

FAQs

What is the effect of PNH on the kidneys?

Long term effects of PNH include chronic kidney disease and can occur after several years of hemoglobinuria. It causes acute tubular-necrosis effects due to:

  • Higher heme and iron (pigment nephropathy)

  • Decreased renal perfusion from renal vein thrombosis

  • Tubular obstruction with pigment casts.

What is the difference between hemoglobinuria and hematuria?

While both conditions result in blood appearing in your urine, it's important to understand what sets them apart. Hematuria refers to the presence of red blood cells in your urine, imparting a red color. On the other hand, hemoglobinuria is characterized by the presence of hemoglobin in your urine, which also gives it a red hue.

Why should you book a HAM's Test-PNH Work Up with Sterling Accuris?

Sterling Diagnostics has highly experienced pathologists and uses the best facilities to provide precise and timely results. Book the HAM's Test-PNH Work Up in Petlad with us.

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