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Why should I book a Microsatellite Instability (PCR) Test with Sterling Accuris Diagnostics ?

Sterling Accuris Diagnostics is at the forefront of pathology services in India, with international quality standards. Our NABL-accredited laboratory specializes in providing quick and reliable primary diagnosis support for hospitals, physicians and other healthcare facilities across the country. 

It is extremely convenient to book a Microsatellite Instability (PCR) Test with us that would give you accurate and precise results at a great price.

How often is MSI unstable?

Cancer cells with significant microsatellite instability could be less able to rectify errors in DNA replication. Colorectal, gastric, and endometrial cancers are the ones where microsatellite instability is most frequently observed, but it can occur in a wide variety of other cancers as well. 

What makes Sterling Accuris a better pathology lab than others?

For us, precision care, safe sample collection, timely delivery of reports, and precise reporting of patient results while adhering to health and safety precautions are the cornerstone of our success.

What other packages does Sterling Accuris offer?

Sterling Accuris offers a range of packages including Senior citizen (male and female) package, healthy heart profile, diabetes profile, vitamin profile, covid immunity package and much more. Visit our website to learn more about these packages.

Do you provide home visit/collection service?

Yes. We do provide home collection services at your doorstep.

Please go ahead and book your visit today from our top menu options in this website / chat or do call us on 812 813 0000.

Is there any preparation or precautions for patient before tests or body checkup?

Fasting maybe required in case of a few tests to ensure accurate results. 

In general, it is also advisable to abstain from alcohol and heavy diet at least for 24 hours before any health test. You can see the requirement for each test on the product page on our website / app.

How long does it take to receive test results?

Though most tests are completed and reported within about 24 hours of receiving the sample for testing, certain tests take several days to weeks.

Your soft copy will be sent on registered email id and Whatsapp. Also, you will receive SMS with link to download your report. Also, your report is available on our website / app.

To know the status of the report, you can call our customer care team on 812 813 0000.

Microsatellite Instability (PCR) Test in Petlad

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Sterling Accuris Diagnostics offers the Microsatellite Instability (PCR) Test in Petlad to identify malignancies brought on by malfunctioning MMR by comparing the number of nucleotides repeats in a panel of microsatellite markers in normal tissue with the amount from tumour tissue from the same individual. 

Overview of Microsatellite Instability (PCR) Test

Mismatch repair (MMR)-defective tumours are detected via MSI testing. MMR-deficient tumours are more likely to accumulate insertion and deletion mistakes in microsatellites because insertion and deletion errors frequently happen during the replication of repetitive DNA sequences. Using fluorescently labelled primers, fragments from the tumour and matching normal samples are amplified in order to identify MSI. The test is a supplement to MMR testing by IHC, and it can spot a unique MSI-High (MSI-H) tumour that has persistent nuclear expression of all 4 MMR genes by IHC.

Get a Microsatellite Instability (PCR) test near you to rule out any further complications that may lead to serious diseases. For accurate and precise test results head on to Sterling Accuris Diagnostics for the Microsatellite Instability (PCR) Test in Petlad.

Why and when is the Microsatellite Instability (PCR) Test done?

In the following circumstances, pathologists ought to request PCR-based MSI testing:

  • MMR IHC results are unclear or suspect.
  • There is a possibility of familial cancer syndrome, although IHC showed that the MMR genes were still expressed.

For all newly diagnosed cases of colorectal cancer, MSI analysis and/or mismatch repair (MMR) IHC are advised in order to identify patients who are more likely to have germline mutations linked to Lynch syndrome (HNPCC). Additionally, in sporadic colorectal cancer, MSI may indicate a better prognosis. When choosing particular immuno-oncology treatments for a variety of solid tumours, MSI and MMR testing also function as companion diagnostic tests. Use to locate cancers with high microsatellite instability (MSI-H) to assess possible eligibility for immunotherapy.

Microsatellite Instability (PCR) Test: Main Highlights

  • Instructions: No specific preparation is required for this test.
  • Recommended Age: Any age group.
  • Sample type for test: Peripheral blood or Tissue slides of tumour tissue and non-tumour tissue.

Understanding how to interpret Microsatellite Instability (PCR) Test Reports 

A high MSI (MSI-H) result could mean that the patient has hereditary nonpolyposis colorectal cancer (HNPCC), commonly known as Lynch syndrome and that the patient's gene repair issue is linked to the development of cancer. Microsatellite stability (MSS), low microsatellite instability (MSI-L), and high microsatellite instability (MSI-H) are three categories that can be used to categorize MSI according to frequency.

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