HAMS Test-PNH Work Up in Sanand
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HAMS Test-PNH Work Up1
FAQ
What other packages does Sterling Accuris offer?
Sterling Accuris offers a range of packages including Senior citizen (male and female) package, healthy heart profile, diabetes profile, vitamin profile, covid immunity package and much more. Visit our website to learn more about these packages.
What makes Sterling Accuris a better pathology lab than others?
For us, precision care, safe sample collection, timely delivery of reports, and precise reporting of patient results while adhering to health and safety precautions are the cornerstone of our success.
Do you provide home visit/collection service?
Yes. We do provide home collection services at your doorstep.
Please go ahead and book your visit today from our top menu options in this website / chat or do call us on 812 813 0000.
How long does it take to receive test results?
Though most tests are completed and reported within about 24 hours of receiving the sample for testing, certain tests take several days to weeks.
Your soft copy will be sent on registered email id and Whatsapp. Also, you will receive SMS with link to download your report. Also, your report is available on our website / app.
To know the status of the report, you can call our customer care team on 812 813 0000.
Is there any preparation or precautions for patient before tests or body checkup?
Fasting maybe required in case of a few tests to ensure accurate results.
In general, it is also advisable to abstain from alcohol and heavy diet at least for 24 hours before any health test. You can see the requirement for each test on the product page on our website / app.
HAM's Test-PNH Workup in Sanand
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Sterling Accuris Diagnostics offers the HAM's Test-PNH Workup in Sanand to diagnose Paroxysmal nocturnal hemoglobinuria (PNH).
Overview of the HAM's Test-PNH Workup
The HAM's Test-PNH Workup is done to detect certain acquired and congenital blood disorders and Paroxysmal Nocturnal Hemoglobinuria (PNH). PNH is a rare disease with a variety of clinical manifestations which include hemolytic anemia and hemoglobinuria, the most common form.
The term comes from:
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Paroxysmal refers to a sudden and irregular occurrence.
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Nocturnal means that the phenomenon takes place at night.
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Hemoglobinuria describes the presence of hemoglobin in urine, which turns it dark in color.
This disorder occurs because of a genetic mutation in the phosphatidylinositol glycan class A (PIGA) gene of hematopoietic stem cells. This in turn results in a deficiency in the glycosylphosphatidylinositol (GPI) protein, which is required for attaching other protein moieties on red blood cell’s (RBC’s) surface. The disease PNH is rare but when present, it can considerably affect the quality of life of the person.
Sterling Accuris Diagnostics offers a reliable HAM's Test-PNH Workup in Sanand with timely reports.
Why And When Is A HAM's Test-PNH Workup Done?
The HAM's Test-PNH WorkUp identifies PNH and its various clinical manifestations.
A doctor may recommend this workup in the following cases:
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Hemolytic anemia
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Weakness
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Blood in urine
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Dizziness
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Hepatomegaly
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Splenomegaly
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Thrombosis
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Bone marrow failure
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Smooth muscle dystonia
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Renal insufficiency
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Fatigue
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Shortness of breath
HAM's Test-PNH Workup: Main Highlights
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Instructions: Fasting not required
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Recommended age group: All age groups
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Sample type: Blood sample in EDTA tube
How to interpret the HAM's Test-PNH Workup Report
The HAM's Test-PNH WorkUp is done using a blood sample.
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A normal HAM's test result is exhibited by RBCs that don’t become fragile in a specific acid solution. A positive report would result in the RBCs becoming fragile, indicating PNH.
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If PNH workup is normal when CD59 (MIRL), a glycoprotein, and CD55 (DAF) are present. If abnormal, the absence or reduced expression of both CD59 and CD55 on RBCs is diagnostic of PNH.
FAQs
What is the effect of PNH on the kidneys?
Long term effects of PNH include chronic kidney disease and can occur after several years of hemoglobinuria. It causes acute tubular-necrosis effects due to:
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Higher heme and iron (pigment nephropathy)
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Decreased renal perfusion from renal vein thrombosis
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Tubular obstruction with pigment casts.
What is the difference between hemoglobinuria and hematuria?
While both conditions result in blood appearing in your urine, it's important to understand what sets them apart. Hematuria refers to the presence of red blood cells in your urine, imparting a red color. On the other hand, hemoglobinuria is characterized by the presence of hemoglobin in your urine, which also gives it a red hue.
Why should you book a HAM's Test-PNH Work Up with Sterling Accuris?
Sterling Diagnostics has highly experienced pathologists and uses the best facilities to provide precise and timely results. Book the HAM's Test-PNH Work Up in Sanand with us.
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