Best Pathology Lab in India for Blood Test & Full Body Checkup Test Slash PDGFRa mutations in Sanand

PDGFRa mutations in Sanand

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PDGFRA - Alpha Mutation By Fish
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FAQ

What is the PDGFRa mutation?

Gastrointestinal stromal tumours are linked to PDGFRA gene mutations (GISTs).

Does PDGFRA act as an oncogene?

The second most often mutated oncogene in GISTs, after KIT, is PDGFRA.

Why should I book a PDGFRa mutation Test with Sterling Accuris diagnostics?

Sterling Accuris diagnostics is at the forefront of pathology services in India, with international quality standards. Our NABL-accredited laboratory specializes in providing quick and reliable primary diagnosis support for hospitals, physicians and other healthcare facilities across the country. 

It is extremely convenient to book a PDGFRa mutation Test with us that would give you accurate and precise results at a great price.

What makes Sterling Accuris a better pathology lab than others?

For us, precision care, safe sample collection, timely delivery of reports, and precise reporting of patient results while adhering to health and safety precautions are the cornerstone of our success.

What other packages does Sterling Accuris offer?

Sterling Accuris offers a range of packages including Senior citizen (male and female) package, healthy heart profile, diabetes profile, vitamin profile, covid immunity package and much more. Visit our website to learn more about these packages.

Do you provide home visit/collection service?

Yes. We do provide home collection services at your doorstep.

Please go ahead and book your visit today from our top menu options in this website / chat or do call us on 812 813 0000.

Is there any preparation or precautions for patient before tests or body checkup?

Fasting maybe required in case of a few tests to ensure accurate results. 

In general, it is also advisable to abstain from alcohol and heavy diet at least for 24 hours before any health test. You can see the requirement for each test on the product page on our website / app.

How long does it take to receive test results?

Though most tests are completed and reported within about 24 hours of receiving the sample for testing, certain tests take several days to weeks.

Your soft copy will be sent on registered email id and Whatsapp. Also, you will receive SMS with link to download your report. Also, your report is available on our website / app.

To know the status of the report, you can call our customer care team on 812 813 0000.

PDGFRa Mutation Test in Sanand

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Sterling Accuris diagnostics offers PDGFRa Mutation Test in Sanand to detect gastro-intestinal cancers. 

Overview of PDGFRa Mutation Test

The platelet-derived growth factor receptor alpha (PDGFRA) gene codes for the production of this protein, which is a member of the receptor tyrosine kinase family (RTKs). Signal transduction is the mechanism by which receptor tyrosine kinases transfer signals from the cell surface into the cell. A particular protein termed platelet-derived growth factor interacts with (binds) the PDGFRA protein, which is present in the cell membrane of several cell types. This interaction activates the PDGFRA protein, which then switches on (activates) other proteins inside the cell by introducing a specific position-specific cluster of oxygen and phosphorus atoms. Multiple signalling pathways are activated as a result of this activity, which involves a number of proteins. Numerous crucial physiological functions, including cell survival and proliferation, are governed by the signalling pathways that the PDGFRA protein stimulates.

Gastrointestinal stromal tumours are linked to PDGFRA gene mutations (GISTs). GISTs are a particular kind of tumour that develops in the GI system, most frequently in the stomach or small intestine. The stomach is the site of the bulk of GISTs connected to PDGFRA gene mutations.

For accurate and precise test results head on to Sterling Accuris diagnostics for the PDGFRa Mutation Test in   Sanand .

Why and when is the PDGFRa Mutation Test done?

This test is recommended by the doctor to confirm the diagnosis of GIST and is helpful for planning the course of treatment. The mutational analysis test for KIT exons 9 and 11 can be used in conjunction with this mutational analysis. Identification of mutations provides insight into tyrosine kinase inhibitor (TKI) therapeutic sensitivity or resistance. 

In the diagnosis and prognosis of PDGFRA-associated chronic eosinophilic leukaemia and gastrointestinal stromal tumours, a doctor typically recommends this test:

PDGFRa Mutation Test: Main Highlights

  • Instructions: No special preparation is needed.
  • Recommended Age: All age group.
  • Sample type for test: A paraffin block or 10 unstained tissue slides of a tumour.

Understanding how to interpret PDGFRa Mutation Test Reports 

The test's results may be classified as "positive" (the presence of the mutated gene sequence) or "negative" (the abnormal gene sequence is not present). The mutational analysis test for KIT exons 9 and 11 can be used in conjunction with this mutational analysis. To find sequence variants, PCR amplification and repeated bidirectional sequencing are applied to the coding exons 10, 12, 14, and 18 of the PDGFRA gene. This assay has the sensitivity to identify about 10% of cells carrying the PDGFRA mutations in a background of non-mutant cells; therefore, any mutational changes in any exon would be recognised. Below the assay's sensitivity, the mutation cannot be detected. 

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Benefits of Packages with us

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